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Dehydration poses the GREATEST threat to the health of your kidneys and the process of blood purification in your body. This rates as THE most common type of stress we inflict on our kidneys, which are ready and waiting to take on the task of ridding our body of toxins. IF you are feeling thirsty you are ALREADY dehydrated, so make it a point to drink at least eight 8-ounce glasses of water every day - and more if you are working out or perspiring excessively.